RHOG Protein (His tag)

N° du produit ABIN1098313

Détail du produit

Antigène: RHOG (Ras Homolog Family Member G (RHOG))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RHOG protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Rho-related GTP-binding protein RhoG, ARHG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH 8.0, 40% glycerol, 5 MM DTT, 200 mM NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: RHOG (Ras Homolog Family Member G (RHOG))

Autre désignation: RhoG (RHOG Produits)

Synonymes: 2810426G09Rik Protein, Arhg Protein, Sid10750 Protein, ARHG Protein, rhog Protein, zgc:55848 Protein, wu:fk30f01 Protein, arhg Protein, rhoga Protein, zgc:66008 Protein, ras homolog family member G Protein, ras homolog family member Gb Protein, ras homolog family member G S homeolog Protein, ras homolog gene family, member Gd Protein, Rhog Protein, rhogb Protein, RHOG Protein, rhog.S Protein, rhogd Protein

Sujet: RhoG(Ras homology Growth-related) is a member of the Rac subfamily of the Rho family of small G proteins. RhoG is a small monomeric GTP-binding protein (G protein), and is an important component of many intracellular signalling pathways. This protien are required for the formation of membrane ruffles during macropinocytosis. It plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. Like most small G proteins RhoG is involved in a diverse set of cellular signalling mechanisms. In mammalian cells these include cell motility, gene transcription, endocytosis, neurite outgrowth, protection from anoikis and regulation of the neutrophil NADPH oxidase. Recombinant human RhoG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 25.2kDa (225aa) confirmed by MALDI-TOF

NCBI Accession: NP_001656

Pathways: Signalisation RTK