ATG10 Protein (His tag)

N° du produit ABIN1098406

Détail du produit

Antigène: ATG10 (Autophagy Related 10 (ATG10))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ATG10 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 95 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Ubiquitin-like-conjugating enzyme ATG10, APG10, APG10L, pp12616

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol,1 MM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: ATG10 (Autophagy Related 10 (ATG10))

Autre désignation: ATG10 (ATG10 Produits)

Synonymes: APG10 Protein, APG10L Protein, pp12616 Protein, Atg10 Protein, ATG10 Protein, MGC123341 Protein, im:7153729 Protein, zgc:123341 Protein, ATATG10 Protein, autophagy 10 Protein, DDBDRAFT_0190076 Protein, DDBDRAFT_0252608 Protein, DDB_0190076 Protein, DDB_0252608 Protein, 5330424L23Rik Protein, 5430428K15Rik Protein, AI852123 Protein, Agp10 Protein, Apg10l Protein, Apg10p Protein, Atg10l Protein, autophagy related 10 Protein, autophagy-related 10 Protein, AuTophaGy (yeast Atg homolog) Protein, ATG10 autophagy related 10 homolog (S. cerevisiae) Protein, autophagocytosis-associated family protein Protein, E2-like conjugating enzyme Protein, hypothetical protein Protein, autophagy protein 10 Protein, autophagy-related protein 10 Protein, ATG10 Protein, Atg10 Protein, atg-10 Protein, atg10 Protein, CAALFM_C302930WA Protein, APG10 Protein

Sujet: Ubiquitin-like-conjugating enzyme ATG10, also known as ATG10, is a 220 amino acid protein that localizes to the cytoplasm and plays a role in autophagy, specifically functioning as an E2-like enzyme that provides Atg recognition sites during autophagosome synthesis. ATG10 has also been shown to interact with ATG12 in human embryonic kidney cells in the presence of ATG7. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. Recombinant human ATG10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 27.7 kDa (243aa) confirmed by MALDI-TOF

NCBI Accession: NP_113670

Pathways: ER-Nucleus Signaling, Autophagy