NBL1 Protein (His tag)

N° du produit ABIN1098541

Détail du produit

Antigène: NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette NBL1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Neuroblastoma suppressor of tumorigenicity 1, D1S1733E, DAN, DAND1, NB, NO3

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol, 1 MM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))

Autre désignation: NBL1 (NBL1 Produits)

Synonymes: D1S1733E Protein, DAN Protein, DAND1 Protein, NB Protein, NO3 Protein, D4H1S1733E Protein, Dana Protein, dand1 Protein, nbl1-a Protein, no3 Protein, 4.1N Protein, Epb41l1 Protein, NBL1 Protein, mKIAA0338 Protein, C1orf151-NBL1 Protein, dan Protein, zgc:77251 Protein, neuroblastoma 1, DAN family BMP antagonist Protein, neuroblastoma, suppression of tumorigenicity 1 Protein, neuroblastoma 1, DAN family BMP antagonist L homeolog Protein, neuroblastoma suppressor of tumorigenicity 1 Protein, erythrocyte membrane protein band 4.1 like 1 Protein, MINOS1-NBL1 readthrough Protein, NBL1 Protein, Nbl1 Protein, nbl1.L Protein, LOC535280 Protein, Epb41l1 Protein, MINOS1-NBL1 Protein, nbl1 Protein

Sujet: Neuroblastoma suppressor of tumorigenicity 1, also known as NBL1, is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. NBL1 is a candidate as a tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. It is produced in small neurons of the dorsal root ganglion and its expression is activated by MATH-1. Recombinant human NBL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 20 kDa (187aa) confirmed by MALDI-TOF

NCBI Accession: NP_005371