Prohibitin Protein (PHB) (His tag)
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- Antigène Voir toutes Prohibitin (PHB) Protéines
- Prohibitin (PHB)
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Prohibitin protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Pureté
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product PHB Protéine
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- Commentaires
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Synonyms: Prohibitin, PHB1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1 M NaCl
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- Prohibitin (PHB)
- Autre désignation
- PHB (PHB Produits)
- Synonymes
- phb1 Protein, MGC75944 Protein, PHB Protein, Phb Protein, ACYPI000080 Protein, phb Protein, PHB1 Protein, Bap32 Protein, sr:nyz128 Protein, wu:fa18f07 Protein, wu:fb09f05 Protein, prohibitin1 Protein, xphb1 Protein, prohibitin Protein, prohibitin-2 Protein, prohibitin L homeolog Protein, PHB Protein, phb Protein, LOC484431 Protein, LOC5576054 Protein, Phb Protein, phb.L Protein
- Sujet
- PHB is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA. Recombinant human PHB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Poids moléculaire
- 31.9 kDa(292aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_002625
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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