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Prohibitin Protein (PHB) (His tag)

PHB Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
N° du produit ABIN1098557
  • Antigène Voir toutes Prohibitin (PHB) Protéines
    Prohibitin (PHB)
    Type de proteíne
    Recombinant
    Origine
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Source
    • 8
    • 4
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette Prohibitin protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Purification
    purified by chromatography
    Pureté
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product PHB Protéine
  • Commentaires

    Synonyms: Prohibitin, PHB1

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1 M NaCl
    Stock
    4 °C
    Stockage commentaire
    Avoid repeated freezing and thawing cycles.
  • Antigène
    Prohibitin (PHB)
    Autre désignation
    PHB (PHB Produits)
    Synonymes
    phb1 Protein, MGC75944 Protein, PHB Protein, Phb Protein, ACYPI000080 Protein, phb Protein, PHB1 Protein, Bap32 Protein, sr:nyz128 Protein, wu:fa18f07 Protein, wu:fb09f05 Protein, prohibitin1 Protein, xphb1 Protein, prohibitin Protein, prohibitin-2 Protein, prohibitin L homeolog Protein, PHB Protein, phb Protein, LOC484431 Protein, LOC5576054 Protein, Phb Protein, phb.L Protein
    Sujet
    PHB is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA. Recombinant human PHB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Poids moléculaire
    31.9 kDa(292aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_002625
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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