EYA2 Protein (His tag)

N° du produit ABIN1098596

Détail du produit

Antigène: EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette EYA2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by using conventional chromatography.

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Eyes absent homolog 2, EAB1, MGC10614

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.15 M NaCl, 1 MM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))

Autre désignation: EYA2 (EYA2 Produits)

Synonymes: EYA2 Protein, zgc:92279 Protein, eab1 Protein, Eab1 Protein, EAB1 Protein, EYA transcriptional coactivator and phosphatase 2 Protein, EYA2 Protein, eya2 Protein, Eya2 Protein

Sujet: EYA2, also known as eyes absent homolog 2, is a member of tyrosine phosphatase family that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). This protein promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Recombinant human EYA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Poids moléculaire: 33.2 kDa (295aa), confirmed by MALDI-TOF