PD-L1 Protein (His tag)

N° du produit ABIN1098649

Détail du produit

Antigène: PD-L1 (CD274 (PD-L1))

Type de proteíne: Recombinant

Origine: Souris

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PD-L1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by using conventional chromatography.

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: CD274 antigen, A530045L16Rik, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.15 M NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: PD-L1 (CD274 (PD-L1))

Autre désignation: CD274 (PD-L1 Produits)

Synonymes: B7-H Protein, B7H1 Protein, PD-L1 Protein, PDCD1L1 Protein, PDCD1LG1 Protein, PDL1 Protein, A530045L16Rik Protein, B7h1 Protein, Pdcd1l1 Protein, Pdcd1lg1 Protein, Pdl1 Protein, RGD1566211 Protein, CD274 molecule Protein, CD274 antigen Protein, programmed cell death 1 ligand 2 Protein, CD274 Protein, Cd274 Protein, PDCD1LG2 Protein

Sujet: CD274, also known as programmed cell death 1 ligand 1(PDCD1L1), is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. This protein interacts with PDCD1 inhibits T-cell proliferation and cytokine production. Recombinant mouse CD274 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Poids moléculaire: 27.6kDa(246aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

NCBI Accession: NP_068693

Pathways: Cancer Immune Checkpoints