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RCAN3 Protein (His tag)

RCAN3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN1098701
  • Antigène Voir toutes RCAN3 Protéines
    RCAN3 (RCAN Family Member 3 (RCAN3))
    Type de proteíne
    Recombinant
    Origine
    • 3
    • 1
    • 1
    Humain
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette RCAN3 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Pureté
    > 90 % by SDS - PAGE
  • Commentaires

    Synonyms: Calcipressin-3, DSCR1L2, hRCN3, MCIP3, RCN3

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 20% glycerol, 0.2 M NaCl
    Stock
    4 °C
    Stockage commentaire
    Avoid repeated freezing and thawing cycles.
  • Antigène
    RCAN3 (RCAN Family Member 3 (RCAN3))
    Autre désignation
    RCAN3 (RCAN3 Produits)
    Synonymes
    DSCR1L2 Protein, rcn3 Protein, hrcn3 Protein, mcip3 Protein, dscr1l2 Protein, MGC145788 Protein, MCIP3 Protein, RCN3 Protein, hRCN3 Protein, Dscr1l2 Protein, AU041093 Protein, Csp3 Protein, wu:fc68f05 Protein, zgc:113155 Protein, zgc:91820 Protein, RCAN family member 3 Protein, calcipressin-3 Protein, regulator of calcineurin 3 Protein, RCAN3 Protein, Tsp_08182 Protein, rcan3 Protein, Rcan3 Protein
    Sujet
    Calcipressin-3, also known as RCAN3, is a 241 amino acid protein that potentially is involved in central nervous system development. RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Overexpression of calcipressin-3 results in inhibition of calcineurin activity towards the nuclear factor of activated T-cells (NFAT) transcription factors and also downregulates NFAT-dependent cytokine gene expression in activated Jurkat T-cells. Highest expression occurs in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Recombinant human RCAN3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    Poids moléculaire
    23.5 kDa (209aa)
    NCBI Accession
    NP_038469
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