CDK5 Protein (His tag)

N° du produit ABIN1098713

Détail du produit

Antigène: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CDK5 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Cyclin-dependent kinase 5, PSSALRE

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4 M Urea

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Autre désignation: CDK5 (CDK5 Produits)

Synonymes: PSSALRE Protein, AW048668 Protein, Crk6 Protein, CDK5 Protein, CG8203 Protein, DmCdk5 Protein, Dmel\\CG8203 Protein, cdk5 Protein, zgc:101604 Protein, cyclin dependent kinase 5 Protein, cyclin-dependent kinase 5 Protein, Cyclin-dependent kinase 5 Protein, cyclin-dependent kinase 5 L homeolog Protein, Cyclin-dependent-like kinase 5 Protein, CDK5 Protein, Cdk5 Protein, cdk5 Protein, cdk5.L Protein, cdk-5 Protein

Sujet: CDK5, also known as cell division protein kinase 5, is a member of the cyclin-dependent kinase family. It is required for proper development of the brain and to be activated, CDK5 must associate with CDK5R1 or CDK5R2. Unlike other cyclin dependent kinases, it does not also require phosphorylation on the T loop so that binding with the activator is sufficient to activate the kinase. This protein is involved in the processes of neuronal maturation and migration, phosphorylating the key intracellular adaptor of the reelin signaling chain. Recombinant human CDK5 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 35.8 kDa(316aa)

NCBI Accession: NP_004926

Pathways: Cycle Cellulaire, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis