ESM1 Protein (His tag)

N° du produit ABIN1098721

Détail du produit

Antigène: ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ESM1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Endothelial cell-specific molecule 1, endocan

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 10% glycerol

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))

Autre désignation: ESM1 (ESM1 Produits)

Synonymes: ESM1 Protein, zgc:153027 Protein, 0610042H23Rik Protein, AV004503 Protein, ESM-1 Protein, Pg25 Protein, endocan Protein, endothelial cell specific molecule 1 Protein, endothelial cell-specific molecule 1 Protein, ESM1 Protein, esm1 Protein, Esm1 Protein

Sujet: Endothelial cell-specific molecule 1, also known as ESM1, is a proteoglycan secreted by endothelial cells and its mRNA expression is regulated by inflammatory cytokines. ESM1 expression has also been detected in different epithelia and in adipocytes. The expression of endocan is upregulated by TNF alpha, IL1 beta, or lipopolysaccharide and downregulated by IFN gamma. Genetically engineered cells overexpressing endocan has been shown to induce tumor formation, suggesting that ESM1 may be involved in the pathophysiology of tumor growth in vivo. Recombinant human ESM1 protein, fused to His-tag at N-terminus, was expressed in E.coli

Poids moléculaire: 20.5 kDa (188aa)

NCBI Accession: NP_008967

Pathways: Growth Factor Binding