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DLL4 Protein (AA 1-532, Extracellular Domain) (Fc Tag)

DLL4 Origine: Souris Hôte: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS Active
N° du produit ABIN1344207
  • Antigène Voir toutes DLL4 Protéines
    DLL4 (delta-Like 4 (DLL4))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    Extracellular Domain, AA 1-532
    Origine
    • 13
    • 4
    • 3
    Souris
    Source
    • 8
    • 5
    • 5
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette DLL4 protéine est marqué à la Fc Tag.
    Application
    SDS-PAGE (SDS)
     Réactivité croisée
    Souris
    Attributs du produit
    Signal peptide and extracellular domain of mouse DLL4 (aa 1-532) is fused at the C-terminus to the Fc portion of human IgG1.
    Pureté
    >90 % (SDS-PAGE)
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product DLL4 Protéine
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Commentaires

    Inhibits adipogenesis of 3T3L-1 cells.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Working aliquots are stable for up to 3 months when stored at -20°C.
    Date de péremption
    3 months
  • Antigène
    DLL4 (delta-Like 4 (DLL4))
    Autre désignation
    DLL4 (DLL4 Produits)
    Synonymes
    hdelta2 Protein, Delta4 Protein, si:ch211-244p18.5 Protein, zgc:136596 Protein, delta like canonical Notch ligand 4 Protein, delta-like 4 (Drosophila) Protein, DLL4 Protein, Dll4 Protein, dll4 Protein
    Sujet
    The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
    Poids moléculaire
    ~95kDa (SDS-PAGE)
    UniProt
    Q9JI71
    Pathways
    Signalisation Notch
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