DLL4 Protein (AA 1-532, Extracellular Domain) (Fc Tag)
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- Antigène Voir toutes DLL4 Protéines
- DLL4 (delta-Like 4 (DLL4))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- Extracellular Domain, AA 1-532
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette DLL4 protéine est marqué à la Fc Tag.
- Application
- SDS-PAGE (SDS)
- Réactivité croisée
- Souris
- Attributs du produit
- Signal peptide and extracellular domain of mouse DLL4 (aa 1-532) is fused at the C-terminus to the Fc portion of human IgG1.
- Pureté
- >90 % (SDS-PAGE)
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product DLL4 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Inhibits adipogenesis of 3T3L-1 cells.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Date de péremption
- 3 months
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- Antigène
- DLL4 (delta-Like 4 (DLL4))
- Autre désignation
- DLL4 (DLL4 Produits)
- Synonymes
- hdelta2 Protein, Delta4 Protein, si:ch211-244p18.5 Protein, zgc:136596 Protein, delta like canonical Notch ligand 4 Protein, delta-like 4 (Drosophila) Protein, DLL4 Protein, Dll4 Protein, dll4 Protein
- Sujet
- The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
- Poids moléculaire
- ~95kDa (SDS-PAGE)
- UniProt
- Q9JI71
- Pathways
- Signalisation Notch
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