CSF2RA Protein (AA 23-320) (His tag)

N° du produit ABIN1691393

Détail du produit

Antigène: CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))

Type de proteíne: Recombinant

Attributs du protein: AA 23-320

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette CSF2RA protéine est marqué à la His tag.

Fonction: Recombinant Human GM-CSF R α/CSF2RA/CD116 (C-6His)

Séquence: EKSDLRTVAP ASSLNVRFDS RTMNLSWDCQ ENTTFSKCFL TDKKNRVVEP RLSNNECSCT FREICLHEGV TFEVHVNTSQ RGFQQKLLYP NSGREGTAAQ NFSCFIYNAD LMNCTWARGP TAPRDVQYFL YIRNSKRRRE IRCPYYIQDS GTHVGCHLDN LSGLTSRNYF LVNGTSREIG IQFFDSLLDT KKIERFNPPS NVTVRCNTTH CLVRWKQPRT YQKLSYLDFQ YQLDVHRKNT QPGTENLLIN VSGDLENRYN FPSSEPRAKH SVKIRAADVR ILNWSSWSEA IEFGSDDGVD HHHHHH

Attributs du produit: Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit alpha/CSF2RA is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu23-Gly320) of Human CSF2RA fused with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))

Autre désignation: CSF2RA (CSF2RA Produits)

Synonymes: CD116 Protein, CDw116 Protein, CSF2R Protein, CSF2RAX Protein, CSF2RAY Protein, CSF2RX Protein, CSF2RY Protein, GM-CSF-R-alpha Protein, GMCSFR Protein, GMR Protein, SMDP4 Protein, Csfgmra Protein, GM-CSF-Ra Protein, GM-CSFR Protein, colony stimulating factor 2 receptor, alpha Protein, colony stimulating factor 2 receptor alpha subunit Protein, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) Protein, CSF2RA Protein, Csf2ra Protein

Sub Type: Fusionprotein

Sujet: Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit alpha (CSF2RA) is a single-pass type I membrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms being membrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophage colony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4).
Alternative Names: Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit Alpha, GM-CSF-R-Alpha, GMCSFR-Alpha, GMR-Alpha, CDw116, CD116, CSF2RA, CSF2R, CSF2RY

Poids moléculaire: 35.5 kDa

UniProt: P15509

Pathways: Signalistation JAK/STAT