Cytochrome C Protein (AA 2-105) (His tag)
-
- Antigène Voir toutes Cytochrome C (CYCS) Protéines
- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 2-105
-
Origine
- Humain
-
Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette Cytochrome C protéine est marqué à la His tag.
- Fonction
- Recombinant Human Cytochrome C/CYCS (C-6His)
- Séquence
- GDVEKGKKIF IMKCSQCHTV EKGGKHKTGP NLHGLFGRKT GQAPGYSYTA ANKNKGIIWG EDTLMEYLEN PKKYIPGTKM IFVGIKKKEE RADLIAYLKK ATNELEHHHH HH
- Attributs du produit
- Recombinant Human Cytochrome C/CYCS is produced with our E. coli expression system. The target protein is expressed with sequence (Gly2-Glu105) of Human CYCS fused with a 6His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CYCS Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Reconstitution
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 0.15M NaCl, 20 % Glycerol, pH 8.0.
- Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Stock
- -80 °C
- Stockage commentaire
-
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Date de péremption
- 6 months
-
- Antigène
- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
- Autre désignation
- CYCS (CYCS Produits)
- Synonymes
- CYC Protein, HCS Protein, THC4 Protein, cyct Protein, cyc Protein, hcs Protein, CYCS Protein, cytc Protein, CYCSA Protein, CG17903 Protein, Cyt C Protein, Cyt c Protein, Cyt-c2 Protein, CytC-2 Protein, Cytc Protein, Cytc-p Protein, DC4 Protein, DMc01 Protein, Dmel\\CG17903 Protein, cyt c Protein, cyt c-p Protein, cyt-c-p Protein, cyt-c2 Protein, cyt.c Protein, cytochrome c Protein, dc4 Protein, pDMc01 Protein, wu:fk52b01 Protein, zgc:86706 Protein, ENSMUSG00000058927 Protein, cytochrome c, somatic Protein, cytochrome c, somatic S homeolog Protein, Cytochrome c proximal Protein, cytochrome c, somatic b Protein, cytochrome c, somatic pseudogene Protein, cytochrome c-like Protein, cytochrome c Protein, CYCS Protein, cycs.S Protein, cycs Protein, Cycs Protein, Cyt-c-p Protein, cycsb Protein, Gm10053 Protein, LOC100724240 Protein, CYC Protein, LOC100847700 Protein, LOC101107954 Protein, LOC106829744 Protein, LOC106992390 Protein, LOC102085712 Protein
- Sub Type
- Fusionprotein
- Sujet
-
Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as a central component of the electron transport chain in mitochondria. CYCS transfers electrons between Complexes III (Coenzyme Q - Cyt C reductase) and IV (Cyt C oxidase). CYCS plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of Cytochrome C to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Alternative Names: Cytochrome C, CYCS, CYC - Poids moléculaire
- 12.8 kDa
- UniProt
- P99999
- Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
-