CGRP Protein (AA 58-141) (His tag)

N° du produit ABIN1692415

Détail du produit

Antigène: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Type de proteíne: Recombinant

Attributs du protein: AA 58-141

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CGRP protéine est marqué à la His tag.

Fonction: Recombinant Human Calcitonin/CALCA (C-6His, E. coli)

Séquence: YVQMKASELE QEQEREGSSL DSPRSKRCGN LSTCMLGTYT QDFNKFHTFP QTAIGVGAPG KKRDMSSDLE RDHRPHVSMP QNANVEHHHH HH

Attributs du produit: Recombinant Human Calcitonin/CALCA is produced with our E. coli expression system. The target protein is expressed with sequence (Tyr58-Asn141) of Human CALCA fused with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,50 % Glycerol, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Autre désignation: CALCA (CALCA Produits)

Synonymes: CALC1 Protein, CGRP Protein, CGRP-I Protein, CGRP1 Protein, CT Protein, KC Protein, CALC Protein, CALCA Protein, CALC3 Protein, ci-ct Protein, calca Protein, CA Protein, CGRP-1 Protein, Calc Protein, Calc1 Protein, Cgrp Protein, Ct Protein, Ctn Protein, calcitonin Protein, CAL6 Protein, Cal1 Protein, RATCAL6 Protein, CGRPI Protein, calc Protein, cgrp Protein, zgc:92886 Protein, calcitonin related polypeptide alpha Protein, calcitonin related polypeptide beta Protein, calcitonin-related polypeptide alpha Protein, calcitonin Protein, calcitonin/calcitonin-related polypeptide, alpha Protein, calcitonin-related polypeptide beta Protein, calcitonin gene-related peptide 2 Protein, CALCA Protein, CALCB Protein, ci-ct Protein, calca Protein, Calca Protein, LOC100008771 Protein

Sub Type: Fusionprotein

Sujet: Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Alternative Names: Calcitonin, Katacalcin, Calcitonin Carboxyl-Terminal Peptide, CCP, PDN-21, CALCA, CALC1

Poids moléculaire: 10.5 kDa

UniProt: P01258

Pathways: Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour