proBNP Protéine

N° du produit ABIN1880436

Détail du produit

Antigène: proBNP (Pro-Brain Natriuretic Peptide (proBNP))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % by SDS-PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS (pH 7.5)

Agent conservateur: Without preservative

Stock: 4 °C

Détail du antigène

Antigène: proBNP (Pro-Brain Natriuretic Peptide (proBNP))

Autre désignation: Pro-BNP (proBNP Produits)

Synonymes: BNP Protein, natriuretic peptide B Protein, NPPB Protein

Sujet: Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes). The release of BNP is modulated by calcium ions. BNP is released from the cardiac ventricles in response to increased wall tension. Rapid measurement of BNP is useful in establishing or excluding the diagnosis of congestive heart failure in patients with acute dyspnea. BNP is secreted along with a 76 amino acid N-terminal fragment (NT-proBNP) which is biologically inactive. BNP binds to and activates the atrial natriuretic factor receptors NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity.

Poids moléculaire: 17 kDa