Recombinant Human Tumor necrosis factor receptor superfamily member 13B/TNFRSF13B is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-His166) of Human TNFRSF13B fused with a polyhistidine tag and FC tag at the C-terminus.
Pureté
> 95 % as determined by reducing SDS-PAGE.
Stérilité
0.2 μm filtered
niveau d'endotoxine
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
TNFRSF13B
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
TNFRSF13B
Origine: Souris
Hôte: Tobacco (Nicotiana tabacum)
Recombinant
≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, ELISA, WB
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Conseil sur la manipulation
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Stock
4 °C/-20 °C/-80 °C
Stockage commentaire
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Date de péremption
3 months
Antigène
TACI (TNFRSF13B)
(Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), is also known as Transmembrane activator and CAML interactorand, CD267 and TACI. TNFRSF13B is a transmembrane receptor protein found predominantly on the surface of B cells, which are an important part of the immune system. TNFRSF13B is highly expressed in spleen, small intestine, thymus and peripheral blood leukocytes. TNFRSF13B mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. TNFRSF13B is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. Defects in TNFRSF13B are the cause of immunodeficiency common variable type 2 (CVID2) and cause of immunoglobulin A deficiency 2 (IGAD2). Alternative Names: Tumor necrosis factor receptor superfamily member 13B, TNFRSF13B, Transmembrane activator, CAML interactorand, CD267,TACI.