S100A8 Protein (AA 1-89) (His tag)

N° du produit ABIN2115335

Détail du produit

Antigène: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Type de proteíne: Recombinant

Attributs du protein: AA 1-89

Origine: Souris

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette S100A8 protéine est marqué à la His tag.

Fonction: Recombinant Mouse S100 Calcium Binding Protein A8/S100A8 (C-6His)

Séquence: MATELEKALS NVIEVYHNYS GIKGNHHALY RDDFRKMVTT ECPQFVQNKN TESLFKELDV NSDNAINFEE FLVLVIRVGV AAHKDSHKEL EHHHHHH

Attributs du produit: Recombinant Mouse Protein S100-A8 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Glu89) of Mouse Mrp8 fused with a 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mMTris, pH 8.0.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: S100A8 (S100 Calcium Binding Protein A8 (S100A8))

Autre désignation: Mrp8 (S100A8 Produits)

Synonymes: 60B8AG Protein, CAGA Protein, CFAG Protein, CGLA Protein, CP-10 Protein, L1Ag Protein, MA387 Protein, MIF Protein, MRP8 Protein, NIF Protein, P8 Protein, Mrp8 Protein, S100A8 Protein, 60B8Ag Protein, AI323541 Protein, B8Ag Protein, CFAg Protein, Caga Protein, p8 Protein, MRP-8 Protein, S100 calcium binding protein A8 Protein, S100 calcium binding protein A8 (calgranulin A) Protein, S100A8 Protein, S100a8 Protein

Sujet: Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
Synonyms: Protein S100-A8,Calgranulin-A,Chemotactic cytokine CP-10,Leukocyte L1 complex light chain,Migration inhibitory factor-related protein 8,MRP-8,Pro-inflammatory S100 cytokine,S100 calcium-binding protein A8,S100a8,Caga, Mrp8

Poids moléculaire: 11.3 kDa

UniProt: P27005

Pathways: Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins