CNTN2 Protein (AA 31-1012) (His tag)

N° du produit ABIN2180893

Détail du produit

Antigène: CNTN2 (Contactin 2 (Axonal) (CNTN2))

Type de proteíne: Recombinant

Attributs du protein: AA 31-1012

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CNTN2 protéine est marqué à la His tag.

Séquence: AA 31-1012

Attributs du produit: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 109 kDa. The protein migrates as 140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Pureté: >95 % as determined by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Conseil sur la manipulation: Please avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: No activity loss was observed after storage at: 4-8°C for 1 year in lyophilized state 4-8°C for 1 month under sterile conditions after reconstitution -20°C to -70°C for 3 months under sterile conditions after reconstitution

Détail du antigène

Antigène: CNTN2 (Contactin 2 (Axonal) (CNTN2))

Autre désignation: Contactin-2 (CNTN2 Produits)

Synonymes: tag1 Protein, si:dz37k09.2 Protein, CNTN2 Protein, D130012K04Rik Protein, TAG-1 Protein, Tax Protein, AXT Protein, TAX Protein, TAX1 Protein, AXONIN-1 Protein, TAG-564 Protein, TAG1 Protein, contactin 2 Protein, contactin 2 (axonal) Protein, cntn2 Protein, CNTN2 Protein, Cntn2 Protein

Sujet: Contactin-2 is also known as CNTN2, TAX1 (transiently-expressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin-1, and is a member of the immunoglobulin superfamily. CNTN2 consists of six Ig-like domains and four fibronectin type III domains, and is anchored to the membrane by glycosylphosphatidylinositol (GPI), whereas the soluble form can be released by a GPI-specific phospholipase. As a neural cell adhesion molecule expressed by a subset of neuronal populations in the developing CNS and PNS, CNTN2 mediates cell-cell interactions either via homophilic, or heterophilic contacts with various adhesion molecules including NgCAM, NrCAM, NCAM and neurocan. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.

Poids moléculaire: 108.3 kDa

NCBI Accession: NP_005067

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size