IL18BP Protein (Fc Tag)

N° du produit ABIN2566702

Détail du produit

Antigène: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IL18BP protéine est marqué à la Fc Tag.

Application: Western Blotting (WB)

Attributs du produit:

Fusion tag: C-Fc Tag

Pureté: >95 % as determined by SDS-PAGE.

Information d'application

Indications d'application: This recombinant protein can be used for WB. For research use only.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 50 mM tris, 100 mM glycine, pH 7.5

Stock: -80 °C,-20 °C

Stockage commentaire: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Détail du antigène

Antigène: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Autre désignation: IL18 BP (IL18BP Produits)

Synonymes: IL18BP Protein, IL-18BP Protein, Igifbp Protein, MC54L Protein, IL18BPa Protein, interleukin 18 binding protein Protein, IL18BP Protein, Il18bp Protein

Sujet: Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.

Poids moléculaire: 44.3 kDa

ID gène: 10068

NCBI Accession: NP_001138529

UniProt: O95998