Lamin A/C Protein (LMNA) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2712309

Détail du produit

Antigène: Lamin A/C (LMNA)

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Lamin A/C protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Lamin-A/C (LMNA) (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Lamin A/C (LMNA)

Autre désignation: Lamin-A/c (Lmna) (LMNA Produits)

Synonymes: CDCD1 Protein, CDDC Protein, CMD1A Protein, CMT2B1 Protein, EMD2 Protein, FPL Protein, FPLD Protein, FPLD2 Protein, HGPS Protein, IDC Protein, LDP1 Protein, LFP Protein, LGMD1B Protein, LMN1 Protein, LMNC Protein, LMNL1 Protein, PRO1 Protein, Dhe Protein, 2459 Protein, 74/76 Protein, CG6944 Protein, D5 Protein, DM[[O]] Protein, Dm Protein, Dm(0) Protein, Dm0 Protein, Dm1 Protein, Dm2 Protein, DmLamin Protein, DmO Protein, Dm[[0]] Protein, Dm[[1]] Protein, Dm[[2]] Protein, Dm[[mit]] Protein, Dm[[o]] Protein, Dmel\\CG6944 Protein, Dmo Protein, LAM Protein, Lam Dm[[0]] Protein, Lam(Dm0) Protein, LamDm[[0]] Protein, LamDm[[o]] Protein, Lam[[Dm0]] Protein, Lamin Dm[[0]] Protein, jf27 Protein, l(2)04643 Protein, l(2)25Ec Protein, l(2)gdh-7 Protein, l(2)gdh7 Protein, l(2)jf27 Protein, lam Protein, lamDm0 Protein, lamDm[[0]] Protein, lamin Protein, lamin Dm0 Protein, lamin Dm[[0]] Protein, misg Protein, nlam Protein, cb948 Protein, fk66d12 Protein, wu:fk66d12 Protein, lmna-A Protein, fpl Protein, idc Protein, lfp Protein, cddc Protein, emd2 Protein, fpld Protein, hgps Protein, ldp1 Protein, lmn1 Protein, lmnc Protein, pro1 Protein, cdcd1 Protein, cmd1a Protein, cmt2b1 Protein, lgmd1b Protein, Lamin-A Protein, lamin-L(III)-like Protein, lamin A/C Protein, lamin A Protein, Lamin Protein, lamin A/C L homeolog Protein, lamin-L(III)-like Protein, LMNA Protein, Lmna Protein, Lam Protein, lmna Protein, lmna.L Protein, LMINA Protein

Sujet: Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 65 kDa

NCBI Accession: NP_005563

Pathways: Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus