CLCA2 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes CLCA2 Protéines
- CLCA2 (Chloride Channel Accessory 2 (CLCA2))
- Type de proteíne
- Recombinant
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CLCA2 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human CLCA2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CLCA2 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- CLCA2 (Chloride Channel Accessory 2 (CLCA2))
- Autre désignation
- Clca2 (CLCA2 Produits)
- Synonymes
- CACC Protein, CACC3 Protein, CLCRG2 Protein, CaCC-3 Protein, CLCA Protein, Clca4 Protein, rbCLCA Protein, 4732440A06 Protein, AI586120 Protein, Clca2 Protein, chloride channel accessory 2 Protein, calcium-activated chloride channel regulator 2 Protein, chloride channel calcium activated 2 Protein, chloride channel calcium activated 5 Protein, CLCA2 Protein, LOC100081268 Protein, Clca2 Protein, Clca5 Protein
- Sujet
- This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. The encoded protein is autoproteolytically processed to generate N- and C- terminal fragments. Expression of this gene is upregulated by the tumor suppressor protein p53 in response to DNA damage. In breast cancer, expression of this gene is downregulated and the encoded protein may inhibit migration and invasion while promoting mesenchymal-to-epithelial transition in cancer cell lines.
- Poids moléculaire
- 100.6 kDa
- NCBI Accession
- NP_006527
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