ACVR1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714363

Détail du produit

Antigène: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ACVR1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Activin receptor type 1 / ACRV1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Autre désignation: Activin Receptor Type 1 (Acrv1) (ACRV1 Produits)

Synonymes: ACTRI Protein, ACVR1A Protein, ACVRLK2 Protein, ALK2 Protein, FOP Protein, SKR1 Protein, TSRI Protein, ActR-IA Protein, ActR-I Protein, ActRIA Protein, Acvr Protein, Acvrlk2 Protein, Alk-2 Protein, Alk8 Protein, D330013D15Rik Protein, Tsk7L Protein, actri Protein, acvr1 Protein, acvr1-a Protein, acvr1-b Protein, acvr1a Protein, acvrlk2 Protein, alk-2 Protein, alk2 Protein, alk8 Protein, fop Protein, sax Protein, skr1 Protein, tsri Protein, xALK-2 Protein, activin A receptor type 1 Protein, activin A receptor, type 1 Protein, activin A receptor type 1 S homeolog Protein, ACVR1 Protein, Acvr1 Protein, acvr1.S Protein

Sujet: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Poids moléculaire: 55 kDa

NCBI Accession: NP_001096