ARHGEF11 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714890

Détail du produit

Antigène: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ARHGEF11 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ARHGEF11 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ARHGEF11 (rho Guanine Nucleotide Exchange Factor (GEF) 11 (ARHGEF11))

Autre désignation: Arhgef11 (ARHGEF11 Produits)

Synonymes: ARHGEF11 Protein, GTRAP48 Protein, PDZ-RHOGEF Protein, B930073M02 Protein, E130307F09 Protein, PDZ-RhoGEF Protein, Prg Protein, RhoGEF Protein, mKIAA0380 Protein, Gtrap48 Protein, Rho guanine nucleotide exchange factor (GEF) 11 Protein, Rho guanine nucleotide exchange factor 11 Protein, rho guanine nucleotide exchange factor 11 Protein, arhgef11 Protein, ARHGEF11 Protein, Arhgef11 Protein, LOC511220 Protein

Sujet: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

Poids moléculaire: 172.1 kDa

NCBI Accession: NP_937879

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling