ACLY Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2715038

Détail du produit

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ACLY protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ATP-citrate synthase (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ACLY (ATP Citrate Lyase (ACLY))

Autre désignation: Atp-Citrate Synthase (ACLY Produits)

Synonymes: ACLY Protein, DDBDRAFT_0205389 Protein, DDBDRAFT_0235360 Protein, DDB_0205389 Protein, DDB_0235360 Protein, ACL Protein, BcDNA:LD21334 Protein, CG8322 Protein, DmATPCL Protein, Dmel\\CG8322 Protein, anon-WO0140519.179 Protein, dATPCL Protein, l(2)01466 Protein, l(2)k09217 Protein, n(2)k09217 Protein, ATPCL Protein, CLATP Protein, A730098H14Rik Protein, AW538652 Protein, Clatp Protein, acly Protein, cb722 Protein, zgc:92008 Protein, ATP citrate lyase Protein, ATP citrate lyase S homeolog Protein, ATP-citrate synthase Protein, citrate synthase, mitochondrial Protein, atp-citrate synthase Protein, ATP citrate lyase a Protein, ACLY Protein, acly.S Protein, LOC587157 Protein, acly Protein, ATPCL Protein, LOC5564509 Protein, CpipJ_CPIJ010291 Protein, Bm1_26245 Protein, ACL Protein, Acly Protein, aclya Protein

Sujet: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Poids moléculaire: 120.7 kDa

NCBI Accession: NP_001087

Pathways: L'effet Warburg