Bestrophin 1 Protein (BEST1) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2715224

Détail du produit

Antigène: Bestrophin 1 (BEST1)

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Bestrophin 1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Bestrophin-1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Bestrophin 1 (BEST1)

Autre désignation: Bestrophin-1 (BEST1 Produits)

Synonymes: CG6264 Protein, Dbest Protein, Dmel\\CG6264 Protein, anon-WO0118547.380 Protein, best Protein, dBest1 Protein, dbest1 Protein, dmBest1 Protein, BEST1 Protein, VMD2 Protein, best-1 Protein, ARB Protein, BEST Protein, BMD Protein, RP50 Protein, TU15B Protein, Bmd Protein, Vmd2 Protein, mBest1 Protein, Bestrophin 1 Protein, bestrophin 1 Protein, Best1 Protein, BEST1 Protein, best1 Protein, Bm1_25500 Protein

Sujet: This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008].

Poids moléculaire: 67.5 kDa

NCBI Accession: NP_004174