DDX1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2719273

Détail du produit

Antigène: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette DDX1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human DDX1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Lin, Sivakumaran, Jones, Li, Harper, Wei, Jin, Rustanti, Meunier, Spann, Harrich: "A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1." dans: Retrovirology, Vol. 11, pp. 121, (2015) (PubMed).

Détail du antigène

Antigène: DDX1 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 1 (DDX1))

Autre désignation: Ddx1 (DDX1 Produits)

Synonymes: CG9054 Protein, DDX1 Protein, Dbp79E Protein, DmDDX1 Protein, DmRH12 Protein, Dmel\\CG9054 Protein, anon-79E Protein, DBP-RB Protein, UKVH5d Protein, si:ch211-214k9.2 Protein, si:dkey-161f12.1 Protein, AA409185 Protein, Dead-box-1 Protein, DEAD-box helicase 1 Protein, DEAD/H-box helicase 1 L homeolog Protein, DEAD (Asp-Glu-Ala-Asp) box helicase 1 Protein, DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 Protein, Ddx1 Protein, DDX1 Protein, ddx1.L Protein, ddx1 Protein

Sujet: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin.

Poids moléculaire: 82.3 kDa

NCBI Accession: NP_004930

Pathways: Ribonucleoprotein Complex Subunit Organization