POLK Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2719558

Détail du produit

Antigène: POLK (Polymerase (DNA Directed) kappa (POLK))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette POLK protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human DNA polymerase kappa protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: POLK (Polymerase (DNA Directed) kappa (POLK))

Autre désignation: Dna Polymerase kappa (POLK Produits)

Synonymes: DINB1 Protein, DINP Protein, POLQ Protein, Dinb1 Protein, POLK Protein, si:ch211-254o18.3 Protein, DNA polymerase kappa Protein, polymerase (DNA directed) kappa Protein, polymerase (DNA directed), kappa Protein, polymerase (DNA directed) kappa L homeolog Protein, POLK Protein, Polk Protein, polk Protein, Tb11.01.0080 Protein, Tb11.01.0010 Protein, Tb11.01.0020 Protein, Tb11.01.0030 Protein, Tb11.01.0040 Protein, Tb11.01.0050 Protein, Tb11.12.0001 Protein, Tb11.12.0002 Protein, Tb11.12.0003 Protein, polk.L Protein, polk-1 Protein

Sujet: This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients.

Poids moléculaire: 98.6 kDa

NCBI Accession: NP_057302

Pathways: Réparation de l'ADN