FMR1 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes FMR1 Protéines
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette FMR1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human FMR1 / FMRP protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FMR1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
- Autre désignation
- Fmr1,fmrp (FMR1 Produits)
- Synonymes
- AT24755 Protein, BcDNA:GM08679 Protein, CG6203 Protein, Dmel\\CG6203 Protein, EP(3)3517 Protein, FMR Protein, FMR1 Protein, FMRP Protein, FMRp Protein, FXR Protein, Fmrp Protein, cg6203 Protein, dFMR Protein, dFMR1 Protein, dFMRP Protein, dFXR Protein, dFXR1 Protein, dFXRP Protein, dFmr1 Protein, dFmrp Protein, dfmr Protein, dfmr1 Protein, dfxr Protein, dfxr1 Protein, dmfr1 Protein, fmr Protein, fmr1 Protein, FRAXA Protein, POF Protein, POF1 Protein, zFMR1 Protein, Fmr-1 Protein, CG6203 gene product from transcript CG6203-RC Protein, fragile X mental retardation 1 Protein, fragile X mental retardation syndrome 1 Protein, Fmr1 Protein, FMR1 Protein, fmr1 Protein
- Sujet
- The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
- Poids moléculaire
- 71 kDa
- NCBI Accession
- NP_002015
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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