GLE1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2721895

Détail du produit

Antigène: GLE1 (GLE1 RNA Export Mediator (GLE1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GLE1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human GLE1 / GLE1L (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GLE1 (GLE1 RNA Export Mediator (GLE1))

Autre désignation: Gle1,gle1l (GLE1 Produits)

Synonymes: Dmel\\CG14749 Protein, GLE1 Protein, GLE1L Protein, LCCS Protein, LCCS1 Protein, hGLE1 Protein, Gle1l Protein, 4933405K21Rik Protein, AA553313 Protein, CG14749 gene product from transcript CG14749-RA Protein, nucleoporin GLE1 Protein, RNA export factor Gle1 Protein, GLE1, RNA export mediator Protein, GLE1 RNA export mediator Protein, GLE1 RNA export mediator (yeast) Protein, CG14749 Protein, CpipJ_CPIJ014147 Protein, SJAG_03847 Protein, GLE1 Protein, Gle1 Protein

Sujet: This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 79.7 kDa

NCBI Accession: NP_001003722