GSKIP Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2722265

Détail du produit

Antigène: GSKIP (GSK3B interacting protein (GSKIP))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GSKIP protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human GSKIP protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GSKIP (GSK3B interacting protein (GSKIP))

Autre désignation: Gskip (GSKIP Produits)

Synonymes: C14orf129 Protein, 4933433P14Rik Protein, RGD1308470 Protein, C21H14orf129 Protein, C8H14orf129 Protein, wu:fc74a11 Protein, wu:fd02b09 Protein, zgc:55683 Protein, c14orf129 Protein, gskip Protein, GSK3B interacting protein Protein, gsk3b interacting protein Protein, GSK3B interacting protein L homeolog Protein, GSKIP Protein, Gskip Protein, gskip Protein, gskip.L Protein

Sujet: This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.

Poids moléculaire: 15.5 kDa

NCBI Accession: NP_057556