GUCY2D Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2722376

Détail du produit

Antigène: GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GUCY2D protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human GUCY2D / RETGC1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GUCY2D (Guanylate Cyclase 2D, Membrane (Retina-Specific) (GUCY2D))

Autre désignation: Gucy2d,retgc1 (GUCY2D Produits)

Synonymes: GUCY2D Protein, CORD5 Protein, CORD6 Protein, CYGD Protein, GUC1A4 Protein, GUC2D Protein, LCA Protein, LCA1 Protein, RCD2 Protein, RETGC-1 Protein, ROS-GC1 Protein, ROSGC Protein, retGC Protein, guanylate cyclase 2D, retinal Protein, guanylate cyclase 2d Protein, GUCY2D Protein, Gucy2d Protein

Sujet: This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.

Poids moléculaire: 119.9 kDa

NCBI Accession: NP_000171

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction