IKKi/IKKe Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2723361

Détail du produit

Antigène: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IKKi/IKKe protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human IKBKE / IKKE protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Autre désignation: Ikbke,ikke (IKBKE Produits)

Synonymes: zgc:100844 Protein, IKBKE Protein, MGC130907 Protein, IKK-E Protein, IKK-i Protein, IKKE Protein, IKKI Protein, AW558201 Protein, IKKepsilon Protein, Ikki Protein, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon Protein, inhibitor of nuclear factor kappa B kinase subunit epsilon Protein, inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog Protein, inhibitor of kappaB kinase epsilon Protein, IKBKE Protein, ikbke Protein, ikbke.L Protein, Ikbke Protein

Sujet: IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30 % of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009].

Poids moléculaire: 80.3 kDa

NCBI Accession: NP_054721

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades