LZTS2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2725089

Détail du produit

Antigène: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette LZTS2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human LZTS2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))

Autre désignation: Lzts2 (LZTS2 Produits)

Synonymes: lapser1 Protein, MGC89253 Protein, si:dkey-250a11.1 Protein, LAPSER1 Protein, BC014695 Protein, mKIAA1813 Protein, Lapser1 Protein, leucine zipper, putative tumor suppressor 2 Protein, leucine zipper tumor suppressor 2 Protein, leucine zipper, putative tumor suppressor 2a Protein, leucine zipper, putative tumor suppressor 2 S homeolog Protein, lzts2 Protein, LZTS2 Protein, lzts2a Protein, Lzts2 Protein, lzts2.S Protein

Sujet: The protein encoded by this gene belongs to the leucine zipper tumor suppressor family of proteins, which function in transcription regulation and cell cycle control. This family member can repress beta-catenin-mediated transcriptional activation and is a negative regulator of the Wnt signaling pathway. It negatively regulates microtubule severing at centrosomes, and is necessary for central spindle formation and cytokinesis completion. It is implicated in cancer, where it may inhibit cell proliferation and decrease susceptibility to tumor development. Alternative splicing of this gene results in multiple transcript variants.

Poids moléculaire: 72.6 kDa

NCBI Accession: NP_115805