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Muscleblind-Like 2 (Drosophila) (MBNL2) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag) Protein

MBNL2 Origine: Humain Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
N° du produit ABIN2725585
$888.80
Plus frais de port $45.00 et $22.00 pour carboglace
20 μg
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  • Nom de la protéine
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 3
    Origine
    Humain
    Source
    HEK-293 Cells
    Purification/Conjugué
    Cette MBNL2 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Specificité
    Optimal preservation of protein structure, post-translational modifications and functions.
    Attributs du produit
    • Recombinant human MBNL2 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    > 50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Nom de la protéine
    Sujet
    This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.
    Poids moléculaire
    39.2 kDa
    NCBI Accession
    NP_997187
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