MUTYH Protein (His tag)

N° du produit ABIN2726612

Détail du produit

Antigène: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MUTYH protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MUTYH (full length, N-term HIS tag, transcript variant alpha1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Autre désignation: Mutyh (MUTYH Produits)

Synonymes: MUTYH Protein, MGC145569 Protein, CYP2C Protein, MYH Protein, 5730495A01Rik Protein, Mutyha Protein, Mutyhalpha Protein, Mutyhb Protein, Mutyhbeta Protein, Mutyhc Protein, Myh Protein, mutY DNA glycosylase Protein, mutY homolog (E. coli) Protein, A/G-specific adenine DNA glycosylase-like Protein, MUTYH Protein, mutyh Protein, LOC100373318 Protein, Mutyh Protein

Sujet: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 59.9 kDa

NCBI Accession: NP_036354

Pathways: Réparation de l'ADN