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PLK1 Protein (Myc-DYKDDDDK Tag)

PLK1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2729185
  • Antigène Tous les produits PLK1
    PLK1 (Polo-Like Kinase 1 (PLK1))
    Type de proteíne
    Recombinant
    Origine
    • 4
    • 2
    Humain
    Source
    • 2
    • 2
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette PLK1 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human PLK1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    PLK1 (Polo-Like Kinase 1 (PLK1))
    Autre désignation
    Plk1 (PLK1 Produits)
    Synonymes
    PLK Protein, STPK13 Protein, plk Protein, PLK-1 Protein, Plx1 Protein, stpk13 Protein, Plk Protein, cb525 Protein, cb636 Protein, ik:tdsubc_2d1 Protein, wu:fb37g11 Protein, wu:fb76g03 Protein, xx:tdsubc_2d1 Protein, polo like kinase 1 Protein, polo like kinase 1 S homeolog Protein, polo-like kinase 1 Protein, polo-like kinase 1 (Drosophila) Protein, Serine/threonine-protein kinase plk-1 Protein, PLK1 Protein, plk1.S Protein, plk1 Protein, Plk1 Protein, plk-1 Protein
    Sujet
    The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis hence, it is a target for cancer therapy.
    Poids moléculaire
    68.1 kDa
    NCBI Accession
    NP_005021
    Pathways
    Cycle Cellulaire, M Phase
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