PRELP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2729749

Détail du produit

Antigène: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PRELP protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Prolargin / PRELP (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Autre désignation: Prolargin,prelp (PRELP Produits)

Synonymes: 7330409J17Rik Protein, SLRR2A Protein, MST161 Protein, MSTP161 Protein, proline arginine-rich end leucine-rich repeat Protein, proline and arginine rich end leucine rich repeat protein Protein, Prelp Protein, PRELP Protein

Sujet: The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

Poids moléculaire: 41.6 kDa

NCBI Accession: NP_958505

Pathways: Glycosaminoglycan Metabolic Process