PSMF1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes PSMF1 Protéines
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 2
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PSMF1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human PSMF1 / PI31 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PSMF1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
- Autre désignation
- Psmf1,pi31 (PSMF1 Produits)
- Synonymes
- PI31 Protein, AW048666 Protein, BC012260 Protein, zgc:92785 Protein, proteasome inhibitor subunit 1 Protein, proteasome (prosome, macropain) inhibitor subunit 1 Protein, PSMF1 Protein, Psmf1 Protein, psmf1 Protein
- Sujet
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
- Poids moléculaire
- 29.6 kDa
- NCBI Accession
- NP_848693
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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