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PTGIS Protein (Myc-DYKDDDDK Tag)

PTGIS Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2730076
  • Antigène Voir toutes PTGIS Protéines
    PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
    Type de proteíne
    Recombinant
    Origine
    • 4
    • 1
    • 1
    • 1
    Humain
    Source
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette PTGIS protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human PTGIS protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PTGIS Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
    Autre désignation
    Ptgis (PTGIS Produits)
    Synonymes
    CYP8 Protein, CYP8A1 Protein, PGIS Protein, PTGI Protein, Cyp8 Protein, Cyp8a1 Protein, Pgis Protein, ptgisl Protein, PTGIS Protein, prostaglandin I2 synthase Protein, prostaglandin I2 (prostacyclin) synthase Protein, prostacyclin synthase Protein, PTGIS Protein, Ptgis Protein, ptgis Protein, VDBG_06319 Protein
    Sujet
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.
    Poids moléculaire
    56.9 kDa
    NCBI Accession
    NP_000952
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