RAP1A Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2730472

Détail du produit

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RAP1A protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human RAP1A (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Autre désignation: Rap1a (RAP1A Produits)

Synonymes: KREV-1 Protein, KREV1 Protein, RAP1 Protein, SMGP21 Protein, AI848598 Protein, G-22K Protein, Krev-1 Protein, Rap1 Protein, RAP-1A Protein, rap 1A Protein, wu:fc66g06 Protein, zgc:86676 Protein, krev-1 Protein, krev1 Protein, rap1 Protein, RAP1A, member of RAS oncogene family Protein, RAS-related protein 1a Protein, RAP1A, member of RAS oncogene family a Protein, RAP1A, member of RAS oncogene family L homeolog Protein, RAP1A Protein, Rap1a Protein, rap1aa Protein, rap1a.L Protein

Sujet: This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 20.8 kDa

NCBI Accession: NP_002875

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor