RBPJ Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

N° du produit ABIN2730632

Détail du produit

Antigène: RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 3

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RBPJ protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human RBP-J kappa / RBPJ (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))

Autre désignation: Rbp-J Kappa,rbpj (RBPJ Produits)

Synonymes: AOS3 Protein, CBF1 Protein, IGKJRB Protein, IGKJRB1 Protein, KBF2 Protein, RBP-J Protein, RBPJK Protein, RBPSUH Protein, SUH Protein, csl Protein, AI843960 Protein, Igkjrb Protein, Igkrsbp Protein, RBP-J kappa Protein, RBPjk Protein, Rbpsuh Protein, Su(H) Protein, XSu(H) Protein, xsu(h)1 Protein, Su(H)1 Protein, Su(h)A Protein, ik:tdsubc_1e8 Protein, rbpj Protein, rbpsuh Protein, xx:tdsubc_1e8 Protein, Su(H)2 Protein, su(h)B Protein, recombination signal binding protein for immunoglobulin kappa J region Protein, recombination signal binding protein for immunoglobulin kappa J region S homeolog Protein, recombination signal binding protein for immunoglobulin kappa J region a Protein, recombination signal binding protein for immunoglobulin kappa J region b Protein, RBPJ Protein, Rbpj Protein, rbpj.S Protein, rbpja Protein, rbpjb Protein

Sujet: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.

Poids moléculaire: 54 kDa

NCBI Accession: NP_976028

Pathways: Signalisation Notch, Stem Cell Maintenance, Smooth Muscle Cell Migration