RUNX3 Protein (His tag)

N° du produit ABIN2731258

Détail du produit

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette RUNX3 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human RUNX3 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 50 mM Tris,8M Urea, pH 8.0.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Autre désignation: Runx3 (RUNX3 Produits)

Synonymes: runxb Protein, RUNX3 Protein, CBFA3 Protein, frrunx3 Protein, runx3 Protein, aml2 Protein, cbfa3 Protein, pebp2ac Protein, AML2 Protein, Cbfa3 Protein, Pebp2a3 Protein, PEBP2aC Protein, runt-related transcription factor 3 Protein, runt related transcription factor 3 Protein, runt related transcription factor 3 L homeolog Protein, runx3 Protein, RUNX3 Protein, runx3.L Protein, Runx3 Protein

Sujet: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 45.7 kDa

NCBI Accession: NP_001026850