SAV1 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes SAV1 Protéines
- SAV1 (Salvador Homolog 1 (SAV1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette SAV1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human SAV1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SAV1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- SAV1 (Salvador Homolog 1 (SAV1))
- Autre désignation
- Sav1 (SAV1 Produits)
- Synonymes
- SAV Protein, WW45 Protein, WWP4 Protein, 1700040G09Rik Protein, Salv Protein, Sav Protein, Wwp3 Protein, Wwp4 Protein, salvador family WW domain containing protein 1 Protein, salvador family WW domain containing 1 Protein, SAV1 Protein, Sav1 Protein
- Sujet
- WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
- Poids moléculaire
- 44.5 kDa
- NCBI Accession
- NP_068590
- Pathways
- Stem Cell Maintenance
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