CCL17 Protéine

N° du produit ABIN2733238

Détail du produit

Antigène: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func), Protein Interaction (PI), Standard (STD), Antibody Production (AbP)

Specificité: Optimal preservation of protein structure, post-translational modifications and functions.

Attributs du produit:

• Recombinant human TARC / CCL17 protein expressed in E. coli.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: Determined by its ability to chemoattract human T cells using a concentration range of 1.0-10.0 ng/ml.

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Conseil sur la manipulation: Resuspend the protein in the desired concentration in proper buffer

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

Autre désignation: Tarc,ccl17 (CCL17 Produits)

Synonymes: A-152E5.3 Protein, ABCD-2 Protein, SCYA17 Protein, TARC Protein, CCL17 Protein, Abcd-2 Protein, Scya17 Protein, Scya17l Protein, Tarc Protein, abcd2 Protein, C-C motif chemokine ligand 17 Protein, chemokine (C-C motif) ligand 17 Protein, ATP-binding cassette sub-family D member 2 Protein, CCL17 Protein, Ccl17 Protein, LOC100537809 Protein

Sujet: This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

Poids moléculaire: 8 kDa

NCBI Accession: NP_002978