TCF4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2733362

Détail du produit

Antigène: TCF4 (Transcription Factor 4 (TCF4))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TCF4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TCF4 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TCF4 (Transcription Factor 4 (TCF4))

Autre désignation: Tcf4 (TCF4 Produits)

Synonymes: E2-2 Protein, ITF-2 Protein, ITF2 Protein, PTHS Protein, SEF-2 Protein, SEF2 Protein, SEF2-1 Protein, SEF2-1A Protein, SEF2-1B Protein, TCF-4 Protein, bHLHb19 Protein, 5730422P05Rik Protein, ASP-I2 Protein, E2.2 Protein, ITF-2b Protein, ME2 Protein, MITF-2A Protein, MITF-2B Protein, TFE Protein, Tcf-4 Protein, TCF7L2 Protein, XE2 Protein, Xtcf-4 Protein, Xtcf4 Protein, e2-A Protein, tcf-4 Protein, transcription factor 4 Protein, transcription factor 4 S homeolog Protein, TCF4 Protein, Tcf4 Protein, tcf4 Protein, tcf4.S Protein

Sujet: This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to > 50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.

Poids moléculaire: 71.6 kDa

NCBI Accession: NP_001077431

Pathways: Signalisation WNT, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus