VKORC1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes VKORC1 Protéines
- VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 2
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette VKORC1 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human VKORC1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product VKORC1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
- Autre désignation
- Vkorc1 (VKORC1 Produits)
- Synonymes
- MGC89620 Protein, BP1071 Protein, CG33544 Protein, Dmel\\CG33544 Protein, HDC06808 Protein, VKORC1 Protein, EDTP308 Protein, IMAGE3455200 Protein, MST134 Protein, MST576 Protein, VKCFD2 Protein, VKOR Protein, D7Wsu86e Protein, vitamin K epoxide reductase complex, subunit 1 Protein, vitamin K epoxide reductase complex subunit 1 Protein, Vitamin-K epoxide reductase Protein, VKORC1 Protein, vkorc1 Protein, Vkor Protein, Vkorc1 Protein
- Sujet
- This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
- 9.7 kDa
- NCBI Accession
- NP_996560
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