VRK1 Protein (His tag)
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- Antigène Voir toutes VRK1 Protéines
- VRK1 (Vaccinia Related Kinase 1 (VRK1))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette VRK1 protéine est marqué à la His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human VRK1 (full length, N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product VRK1 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- VRK1 (Vaccinia Related Kinase 1 (VRK1))
- Autre désignation
- Vrk1 (VRK1 Produits)
- Synonymes
- vrk1 Protein, MGC64390 Protein, MGC75762 Protein, VRK1 Protein, PCH1 Protein, PCH1A Protein, 51PK Protein, wu:fe16f06 Protein, zgc:56266 Protein, vaccinia related kinase 1 L homeolog Protein, vaccinia related kinase 1 Protein, Serine/threonine-protein kinase VRK1 Protein, vrk1.L Protein, vrk1 Protein, VRK1 Protein, vrk-1 Protein, Vrk1 Protein
- Sujet
- This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 Molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
- Poids moléculaire
- 45.3 kDa
- NCBI Accession
- NP_003375
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