WFS1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2735628

Détail du produit

Antigène: WFS1 (Wolfram Syndrome 1 (WFS1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette WFS1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Wolframin / WFS1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: WFS1 (Wolfram Syndrome 1 (WFS1))

Autre désignation: Wolframin,wfs1 (WFS1 Produits)

Synonymes: WFRS Protein, WFS Protein, WFSL Protein, CG4917 Protein, Dmel\\CG4917 Protein, GB15257 Protein, WFS1 Protein, AI481085 Protein, wolframin Protein, wfs1 Protein, wolframin ER transmembrane glycoprotein Protein, wolfram syndrome 1 Protein, wolframin Protein, Wolfram syndrome 1 (wolframin) L homeolog Protein, Wfs1 Protein, WFS1 Protein, wfs1 Protein, LOC552818 Protein, CpipJ_CPIJ013087 Protein, wfs1.L Protein

Sujet: This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 100.1 kDa

NCBI Accession: NP_005996

Pathways: Sensory Perception of Sound, Carbohydrate Homeostasis, ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome