DLL1 Protein (AA 1-545, Extracellular Domain) (Fc Tag)

N° du produit ABIN2745651

Détail du produit

Antigène: DLL1 (delta-Like 1 (DLL1))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: Extracellular Domain, AA 1-545

Origine: Humain

Source: CHO Cells

Purification/Conjugué: Cette DLL1 protéine est marqué à la Fc Tag.

Application: SDS-PAGE (SDS)

Specificité: Interacts with human Notch1 (as confirmed by flow cytometry).

Réactivité croisée: Humain

Attributs du produit: Signal peptide and extracellular domain of human DLL1 (aa 1-545) are fused at the C-terminus to the Fc portion of human IgG1.

Pureté: >90 % (SDS-PAGE)

niveau d'endotoxine: <0.01EU/μg purified protein (LAL test, Lonza).

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Inhibits adipogenesis of 3T3L-1 cells. Induces the Notch target gene HES-1 when coated on a plate at 1μg/ml.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in distilled water.

Concentration: Lot specific

Buffer: Lyophilized. Contains PBS.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.

Détail du antigène

Antigène: DLL1 (delta-Like 1 (DLL1))

Autre désignation: DLL1 (DLL1 Produits)

Synonymes: X-delta-1 Protein, XDelta1 Protein, Xdelta-1 Protein, delta Protein, delta-1 Protein, delta1 Protein, x-delta Protein, DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, DLL1 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, delta-like 1 Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 L homeolog Protein, delta-like 1 (Drosophila) Protein, delta-like 1 homolog (Drosophila) Protein, dll1 Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, dll1.L Protein, Dlk1 Protein

Sujet: DLL1 (Delta-like protein, Delta1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.

Poids moléculaire: ~100kDa (SDS-PAGE)

UniProt: O00548

Pathways: Signalisation Notch, Stem Cell Maintenance