GZMB Protein (GST tag,His tag)

N° du produit ABIN5505650

Détail du produit

Antigène: GZMB (Granzyme B (GZMB))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette GZMB protéine est marqué à la GST tag,His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Purified recombinant protein of Human granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50 μg (full length, N-term GST tag, C-term His tag) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purification: Purified

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal,N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: granzyme B (GZMB Produits)

Synonymes: CCPI Protein, CGL-1 Protein, CGL1 Protein, CSP-B Protein, CSPB Protein, CTLA1 Protein, CTSGL1 Protein, HLP Protein, SECT Protein, granzyme B Protein, GZMB Protein

Sujet: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis.

Poids moléculaire: 51.5 kDa

NCBI Accession: NP_004122

Pathways: Apoptose, Caspase Cascade in Apoptosis