BDNF Protein (AA 129-247) (His-SUMO Tag)
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- Antigène Voir toutes BDNF Protéines
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 129-247
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette BDNF protéine est marqué à la His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- HSDPARRGEL SVCDSISEWV TAADKKTAVD MSGGTVTVLE KVPVSKGQLK QYFYETKCNP MGYTKEGCRG IDKRHWNSQC RTTQSYVRAL TMDSKKRIGW RFIRIDTSCV CTLTIKRGR
- Purification
- SDS-PAGE
- Pureté
- > 90 %
- Top Product
- Discover our top product BDNF Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Stock
- -80 °C,4 °C,-20 °C
- Stockage commentaire
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Antigène
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Autre désignation
- BDNF (BDNF Produits)
- Synonymes
- ANON2 Protein, BULN2 Protein, bdnf-A Protein, BDNF Protein, bdnf Protein, brain derived neurotrophic factor Protein, brain-derived neurotrophic factor Protein, brain-derived neurotrophic factor L homeolog Protein, brain-derived neurotrophic factor S homeolog Protein, BDNF Protein, Bdnf Protein, bdnf Protein, bdnf.L Protein, bdnf.S Protein
- Sujet
- During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systs. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is phasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
- Poids moléculaire
- 29.5 kDa
- UniProt
- P23560
- Pathways
- Signalisation RTK, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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